Choose your favorite Gerovital product on sale at www.markastore.com - our partner Gerovital Romanian Shop.

• More than 100 products on sale. 
• Quick dispatch and worldwide delivery
• Safe packaging in strong cardboard boxes.

First Gerovital H3 Cream produced at Farmec Cluj was done in 1967 following the special Ana Aslan formula.

Products of the range are hypoallergenic, parabens and colorants free and address both young (age 25+) and mature (age 45+) complexions.
This new line has 12 products ideal for sensitive complexions.

Now you can reduce wrinkles and fine lines with this revolutionary intensive treatment launched by Farmec SA in February 2012.
10 days of treatmentThe Gerovital H3 Evolution Hyaluronic Acid Ampules contain a serum rich in Superoxide Dismutase and pure liposome Hyaluronic Acid, with intensely moisturizing effects and a dual action, restoring the skin’s water reserves and reducing transepidermal water loss.The anti-age effect is also enhanced by Superoxide Dismutase which has a protection role both for the collagen and elastin fibers and for the hyaluronic acid. Used regularly, the product visibly reduces deep wrinkles.For long-lasting effects, apply this treatment every month. Pour the ampule content into the palm of your hand and apply on the freshly cleaned skin by gently massaging it. Once the serum is absorbed, apply the daily care cream from the Gerovital H3 Evolution Prof. Dr. Ana Aslan line.

Hyaluronic Acid is the core substance forming the extracellular matrix and has the capacity to bind large quantities of water, being directly responsible for the skin moisturizing level. The liposomes with Hyaluronic Acid are absorbed into the skin where they release the sodium Hyaluronate which binds a large quantity of water in a tridimensional network, highly increasing its volume. Thus the wrinkles are filled from the inside and are smoothed and the skin becomes firmer. The combination with the high molecular weight pure Hyaluronic Acid ensures the creation of a protective barrier for the skin, which prevents transepidermal water loss.
SOD Superoxide Dismutase Concentrate of high purity is one of the most active and stable antioxidant enzymes of natural origin and it was proven that when applied externally it penetrates the horny layer and restores the antioxidant balance of the epidermis and skin. Superoxide Dismutase has protection and prevention action. By protecting the hyaluronic acids, the collagen and elastin fibers from the oxidant free radicals, the lipids from the lipoperoxidase activity, SOD delays the signs of skin ageing: wrinkle appearance, dehydration the appearance of pigment spots and loss of elasticity.

GEROVITAL H3 EVOLUTION LINE was specially designed to slow down and couteract the long-term effects of all 3 mechanisms of skin aging, using 3 active principles:
SOD (Superoxide Dismutase) also called "the anti-aging super-enzymes" plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Ensures long-term skin firmness, acts against oxidative degradation and protects fibroblasts chains of collagen and elastin proteins which are responsible for skin elasticity. SOD is the most active naturally occurring antioxidant enzyme.
Trylagen is a combination of active peptides and proteins. It provides an efficient treatment to restore the collagen levels of both young and mature skin. Maintains an adequate long-lasting collagen function that will ensure a healthy and youthful skin. Trylagen acts on 3 main functions:

• Collagen boosting
• Collagen organization
• Collagen protection

GP4G (diguanosine-tetra-phosphate) is a unique plankton extract that energizes and protects skin from environmental stress, and enhances maintenance and repair. It is also offers a new way to increase cellular defenses against UV stress. 

Usage: Get the serum entirely at the bottom of the ampule, and then place it with the breaking point forward.
For hand protection, wrap the ampule in a tissue before breaking it!
Use the ampules in the morning or in the evening in a 10-day treatment sessions. Pour the ampule content into the palm of your hand and apply on the freshly cleaned skin by gently massaging it. Once the serum is absorbed, apply the daily care cream from the Gerovital H3 Evolution line. For long-lasting effects, apply this treatment every month.

Gerovital Plant FORTE - Eye Defence Cream   Anti-Wrinkle. Eye Brightener. Dry, Sensitive Skin. WHO IS IT FOR Illuminate the eyes and rejuvenate the skin with this moisturizer. Dry, sensitive skin. WHY DO YOU NEED IT Fades away fine line and reduces wrinkles around eyes. Prevents premature aging and fights free radicals. Nourishes and infuse moisture. Revitalizes, improves tonus and smoothes while showing bright eyes and ageless skin. HOW TO USE IT Every day, morning and evening, after cleansing and toning, massage gently the cream around eyes. WORKS WELL WITH Gerovital Plant - Eye Gentle Cleansing Lotion. KEY INGREDIENTS Elastin and Sepilift vanish away the fine lines and decrease wrinkles. Vitamins A and E block free radicals damages. Squalene, Cocoa Butter and Marigold Oil regenerate and hydrate. Check the product on http://www.markastore.com

Depression represents one of the major problems as the years go.
Depression is a syndrome, a series of symptoms, involving physiological, emotional and cognitive transitions.

Depression Symptoms.
Diagnostic and Statistical Manual of Mental Disorders of the American Psychiatric Associations established a list of symptoms for depression breakdowns:
- change in food appetite;
- modifications in body weight;
- sleep disturbances;
- body constrictions and delayed kinetic responses;
- fatigue and lack of energy;
- anxious, fearful, tense and nervous states;
- memory and concentrations disorders;
- dislike, indifference and aversion for any kind of activity;
- tendency for guilt;
- thought or attempt of suicide;

The presence of 5 symptoms (of 10) shows depression.

Risk factors for Depression.
Principles that increase the occurrence of depression in the elderly include: being female, unmarried (especially if widowed); stressful and solicitant life events; deficit of supportive social network. Having physical conditions like Stroke, Hypertension, Atrial Fibrillation, Diabetes, Cancer or Dementia further aggravates the risk of clinical depression.

The risk factors often see in seniors are:
- certain medicines or combination of drug;
- other disorders and illnesses;
- social disconnection and living alone;
- recent loss of loved one;
- presence of a chronic and severe pain;
- deterioration of the body image (from amputation, cancer surgery, heart attack);
- previous history of depression;
- family cases of major depressive disorders;
- fear of death;
- past suicide attempts;
- substance abuse;

In younger years, depression is ignored. Both physician and patient are concerned about physical diseases.
But, in the old ages, depression develops within a complicated and complex clinical and social context. The patient frequently experience 2, 3 or even more maladies; most of these are related to body infirmity. Also, a fundamental cause for depressive states is that the social relationship doesn’t exist anymore due to the death of a spouse, retirement and/or relocation of residence.
Studies issued that at least 30% of old people are depressive. Others claimed a higher rate – 50%. The percentage progresses as the age increases.
But, these disturbances often remain undisclosed, being hidden under physical sickness. Although, the science and diagnosis expanded to unexpected and remarkable limits, many directions in depression are still unknown.

Age, Illnesses and Depression
Depression in seniors is not considerably different from adult’s depressive state.
But, in the late-life it coexists with multiple medical illnesses and disabilities. The somatic age collapses (cardiovascular, digestive, respiratory, weight loss) set a lot of inquiries for establishing a correct analysis and diagnosis.
Any depressive symptom may undermine life’s quality and life itself. So, a therapy is mandatory.

In 1945, Dr. Aslan started to treat with Procaine injections the patients with painful Arthritis, for healing their joints pain. Many patients showed an improved memory status, less depression, increased energy and a general well-being condition.
These conclusions determined her to continue to study the effects of Procaine on thousands of patients. She realized that by adding an antioxidant to Procaine, the effects were better. So, she did that and she called the improved formula ‘Gerovital H3’. From that period, Gerovital H3 was included on Pre-Geriatric and Geriatric class of medicines and considered a rehabilitator for the aged ones.

Gerovital H3 – Anti-Depressive Therapy

Gerovital H3 improves cells metabolism and has regenerative effects on mental and physical functions of the body. It ameliorates concentration and vitality; it reduces body inflexibility, enhances well-being and acts as an antidepressant.
Gerovital H3 represents a reversible inhibitor of the brain enzyme MAO (Monoamine Oxidase), the substance that increases with age and breaks down neurotransmitters, having so a destructive affect on brain function.

Beginning at 40, for fighting against aging and to prevent chronic ailments, it may be started a precautionary therapy,

PROTOCOL for PREVENTION (Pills Management).
2 tablets/day for 12 days; then, a break for 2 weeks.

- 1 Gerovital H3 pill in 2 hours after breakfast (ex: breakfast at 08.00am, pill at 10.00 am);
- 1 Gerovital H3 pill in 2 hours after lunch (ex: lunch at 12.00, pill at 04.00 pm);

In one year, the schedule consists in 5 series of 25 pills with appropriate breaks.
The plan can be changes to 6 series, if required.

To increase the regenerative actions, the therapy may combine pills with injections.

Gerovital H3 injectable therapy consists in 1.5-2.0mg/kg of body weight. This dose is one per day. This signifies 1 vial (ampoule) of Gerovital H3 per day.

PROTOCOL for REGENERATION and CURE (Pills & Injection Management).

- 3 Gerovital H3 injection/ week for 4 weeks;
- 2 weeks break;
- 2 Gerovital H3 pills/ day for 12 days;
- 2 weeks break;
Then resume the plan.http://www.blogger.com/img/blank.gif

Any other procedure or dose must be decided by the physician. The schedule must be adapted by taking under advisement the patient’s particularities: age and associated diseases.
If the patient forgets to one dose or more, the therapy should be lengthened.
Do not change the dose or schedule by your own decision.
Consult your doctor whenever considered necessary.
Consult your doctor if you think the drug effects are too high or to low.

Buy Online: http://www.markastore.com Official Online Romanian Gerovital products retailer

next: Arthritis and Gerovital H3.

Administration. Restrictions. Therapy Management.

Gerovital H3 is part of the class of drugs that act upon the body, especially in depression, stress and overworking circumstances.
Also, its properties recommend the drug for treating the degenerative diseases (Rheumatism, Arthritis, Parkinson, Arteriosclerosis).

Gerovital H3 is suitable beginning at 40, for holding back and for reversing the aging processes in the human body.

The therapy has both prophylactic and curative directions.
It can be used as a single drug therapy or it can be associated with other medicines.

Gerovital H3 Administration:

The drug must be administrated 2 hours after the meals (either oral or IM-intramuscular injection). After injection, a 10-15 minutes rest is required.

Gerovital H3 Restrictions:

Not recommended in the following cases: severe hepatic conditions; renal failure; severe arterial high blood pressure; febrile states.
It should not be combined with Physostigmine (Eserine), Prostigmin and Sulphamides.

*Physostigmine (Eserine) is a crystalline alkaloid used in medicine as a miotic and cholinergic agent and to enhance memory in patients with Alzheimer's disease.

*Prostigmin is a parasympathetic drug that acts as a reversible inhibitor to acetylcholinesterase, an enzyme which breaks down acetylcholine (ACh) in cholinergic nerve endings. It is used clinically to treat Myasthenia Gravis, Paralytic Ileus and Urine Retention.

*It is advisable not to apply Gerovital H3 in the same time with Sulphamides, because the interaction in the bacterial metabolism.

Consult your physician, especially:
- if you suffer from any disease;
- if you have any form of allergy;
- if you are self-medicating;

Take an allergy test before you start an injection cure.

First, take an ID intradermal injection (1 ml). Also, an IM intramuscular test (2ml).
These tests should reveal any possible allergy to Procaine.

The therapy with Gerovital H3 should be conducted under medical examination, especially at the beginning, in the first sequences of injections. The physician is able to determine an appropriate dose and eventually change, reduce or cancel other medication previously taken.

Gerovital H3 Therapy Management:

Gerovital H3 pills therapy involves 2 tablets per day.

Beginning at 40, for fighting against aging and for preventing chronic illnesses, it may be started a protective therapy,

SCHEDULE for PREVENTION (Pills Management).
2 tablets/day for 12 days; then, a break for 2 weeks.

- 1 Gerovital H3 pill in 2 hours after breakfast (ex: breakfast at 08.00am, pill at 10.00 am);
- 1 Gerovital H3 pill in 2 hours after lunch (ex: lunch at 12.00, pill at 04.00 pm);

In one year, the schedule consists in 5 series of 25 pills with appropriate breaks.


Gerovital H3 injectable therapy consists in 1.5-2.0mg/kg of body weight. This dose is one per day. This signifies 1 vial (ampoule) of Gerovital H3 per day.

SCHEDULE for REGENERATION and CURE (Pills & Injection Management).
- 3 Gerovital H3 injection/ week for 4 weeks;
- 2 weeks break;
- 2 Gerovital H3 pills/ day for 12 days;
- 2 weeks break;
Then resume the plan.

Any other procedure or dose must be decided by the physician. The schedule must be adapted by taking under advisement the patient’s particularities: age and associated diseases.
If the patient forgets to one dose or more, the therapy should be lengthened.
Do not change the dose or schedule by your own decision.
Consult your doctor whenever considered necessary.
Consult your doctor if you think the drug effects are too high or to low.

Gerovital H3 Side Effects:

In rare situations, at the beginning of the therapy, the patient may notice slight vertigo, cephalic heat perception or metallic taste. These disappear during the treatment.
Even after the allergy tests you observed none but later, during the injection therapy, it shows a cutaneous (dermal) reaction, immediately see your doctor.

Important to keep in mind:

- the drug must be administrated after meals;
- after taking an injection, a 10-15 minutes rest is mandatory;
- the product should be stores in a dry place, at room temperature;
- respect the validity date mentioned on the product;
- keep out of children’s reach;

Buy Online:  markastore.com - Official Romanian Gerovital Products retailer

next: Age and Depression. Therapy.

Cutaneous ageing it`s a slowly process , that
starts it` s clinical change perfidious after the
age of 35.

The mainly cause of cutaneous ageing process
is the accumulation of superoxyds (free acids) :
superoyds ions, the hydroxide anion, peroxide of hy-
drogen and the singhalet oxygen.

The free radicals can appear after the cells oxidoreduc-
tion process during the human body normal methabo-
lism, but also they can appear after exhibiting to envi-
ronment pollution, noxas, smoking,
uV radiations, alchool and drugs consmption, after
swells.

The cutaneous ageing is the consequence of two pro-
cesses : the extrinsic ageing ( photo ageing) and the
intrinsic ageing ( the chronological one).
the chronological one has a genetic propensity .
the ageing skin is clinical characterised by losingit`s
normal texture, tonus, resilence and firmness.
the skin becomes thin, translucid and that makes possi-
ble seeing the undernith dilated vessels, that lost their
resilience: teleangiectasia.

It becomes dryed, serous because of the substraction
of sebaceous and sudoriparous secretion with an im-
portant role for maintaining the protective, hidrolipidic
lubricant cutaneous film that ensures skin`s flexibility
and a ph of 4, - , .

It has a pigmentation which is not homogenous -
through the appearance of the lentigo, actinic Kera-
tosis and seborrhoeic Kerastosis especially when one
expose to the sun radiations.

After that we can see the wrinkles: expression wrinkles
and then the deep ones. after losing the hypodermic
grease the cheeks and the eyes widen, the eyelids fall,
it appears the goitre, the superiour lip becomes thin,
the skin looks flabby, depened, and we can see grossly
and vertical wrinkles arond the lips .
the clinical manifestations are the consequence of the
next pathological changes:
● at the epidermic level the capacity of cells renovation
goes down, the epiderm is thin.
● the dermic level is characterised by the decrease of
the collagen and elastic fibras which is caused by fibro-
blasts and growth of colagenosis and methaloprotei-
nasis activity, and also growth of glycosided collagen
the cause for cells death, the derm is atrophied.
● the pigmentattion changes are the consequence of
the lipofuscines accumulation in fibroblasts and the
oresence of melanic cells at the demo-epidermial junc-
tion.

The causative for the superficial wrinkles is the elastic
fibras deterioration.
the expression wrinkles are the consequence of facial
repeated movement with the secondary and frequency
contractions of facial muscles, and from the morfo-
pathological point of view it`s the densification ofder-
moepidermical junction.

The deep wrinkles are caused by the deterioration of
the elastic fibras.
The gravitational wrinkles appear after losing the resi-
lence of the skin and of the cellular hypodermic tissue
the adipose tissue is slided, and the derm is relaxed.

Visit Gerovital H3 Romanian store: markastore.com

Romanian Anti Aging Magazine
Cornelia Rusu, Daniela Gradinaru, Claudia Borsa, Cristina Ionescu
“Ana Aslan” National Institute of Gerontology and Geriatrics, Bucharest, Romania


Ever since 1952, multidisciplinary research on
aging in romania has been initiated as a priority
by professor dr. ana aslan. the priority lies in
three directions established for gerontological research
and acknowledged worldwide since then: clinical in-
vestigations, experimental research and social sciences
research.

At the same time, a large prophylaxis campaign with
Gerovital H3 (GH3) (procaine hydrochloride-2%, ben-
zoic acid-0.12%, disodium phosphate-0.01% and potas-
sium metabisulphite-0.10%, pH 3.3) and Aslavital (pro-
caine hydrochloride-2%, benzoic acid-0.12%, disodium
phosphate and L-glutamic acid potassium salt-1.2% and
potassium metabisulphite-0.10%, pH 3.3) - as procaine
based medication - was launched in the sixties and sev-
enties.
Ana Aslan envisaged and discovered procaine therapeu-
tic actions subsequent to long term treatment in low
doses with curative and preventive roles. as certified
by physicians and researchers, gh and aslavital had
been more effective than procaine from the point of
view of tolerance and efficacy. at cellular and molecu-
lar levels, procaine and its metabolites action sites are
multiple. procaine binds to membrane constituents and
interacts in a series of ion channels.

The compound has influence on metabolic pathways
involving intracellular signal molecules. primary and
secondary metabolites of procaine participate as pre-
cursors in synthesis of essential molecules for cellular
metabolism. procaine, gh and aslavital have antioxidant action:
inhibit reactive oxygen species generation
and lipid peroxidation in enzymatic and nonenzymatic
systems associated with a modulating effect on anti-
oxidant enzymes. gh and aslavital exert their action
on the atherogenesis process by lipid and lipoproteins-
lowering effects, procaine action on the erythrocyte
membrane and by antioxidant mechanisms. gh and
aslavital could be included in the category of revers-
ible and competitive mao inhibitors.

Their clinical use was warranted in studies of depres-
sion carried out in late eighties. gh and aslavital
modulate mechanisms of aging at cellular and molecu-
lar levels, as well as common mechanisms of chronic
degenerative age related diseases. these two romanian
drugs may be considered as marking the next great era
in gerontoprophylaxis.

Find Ana Aslan cosmetics online at markastore.com.