Gerovital H3 Romania

Retinol, retinoic acid and retinyl palmitate are all forms of vitamin A – the term used to cover its various forms and strengths. Retinol is the most active form of Vitamin A and a powerful cosmetic ingredient.



When referring to dietary allowances or nutritional science, retinol is usually measured in international units (IU). IU refers to biological activity and therefore is unique to each individual compound; however 1 IU of retinol is equivalent to approximately 0.3 micrograms (300 nanograms).



Since the first topical retinoid was approved for acne in 1971, these vitamin A products have been hailed by many as a cure for all skin problems. Dermatologists soon noticed that patients on Retin-A (the brand name of the first retinoid—tretinoin – approved by the FDA) experienced not just clearer but softer, brighter, less-lined skin.

Although retinoid moisturizers, gels and liquids may not be the answer to every skin condition, there are several major problems for which their effectiveness is proven.



1. Acne

If you have moderate to severe acne, adding a topical retinoid to your regimen prevent the production of excess oil, helps unclog pores, reduces outbreaks, regulates the natural enzymes of the skin that fight infection and decrease inflammation and increase collagen which helps decreasing acne scarring and wrinkle formation.



2. Wrinkles prevention

Retinol was originally developed as an anti-aging treatment. It lightens discoloration, smoothes skin texture, and boosts collagen production, which will increase skin’s firmness and elasticity.

It works by normalizing the top layer of your skin and it seems to have a wonderful effect even deeper or lower in the skin

Retiniol is considered now cosmetic industry’s top standard anti-aging ingredient because is been proving to actually stimulate and produce collagen in your skin.



3. Pigmentation and discoloration

Pigmentation and discoloration are usually stimulated by factors such as sun exposure and hormonal imbalance. A Retinol regimen can help stimulate cell turnover for younger-looking neutralizing the overproduction of melanin, the pigment that determines our skin tone, reduce discoloration and also protect the skin from future sun damage.




Knowing when and how to use it can be a little confusing.

Some dermatologists say that you’re never too old and you’re never too young to get started using Retinol based products. It can work very well for acne, so teenagers can benefit from it. It depends on the formula and depends on your skin condition.

You just need to respect your dermatologist’ advice, to carefully read and respect manufacturer’s indications and to listen to your skin. Sounds simple, doesn’t it?



Still there some rules associated with Retinol creams usage: they should be applied on a perfectly cleansed skin, paired with a moisturizer and a sunscreen.

Some dermatologists say you should only use it in the evening and avoid sun, but some say that is a myth and point to clinical studies that have shown pretty definitively that retinoids do not lower the MED—or minimal erythemal dos—of human skin, which is the amount of UV light you can take before the skin burns.




Prescription formulas contain retinoic acid, the magic ingredient that fights visible aging; nonprescription alternatives need to be converted into retinoic acid by the skin at the cellular level.

While prescription formulas yield the fastest results due to the highest concentration, cosmetic producer’s biggest challenge is how to make a powerful form and incorporate it in the over-the-counter products.

There's a lot of literature showing that while Retinol is more gentle than retinoic acid, biochemically it does exactly the same thing—it may just take longer to see results. Dermatologists say it takes an average of 12 weeks for retinoic acid to produce noticeable changes in the skin, and even longer for Retinol products. So stick with it for at least that long to see the benefits.




Is there a downside after so many great benefits? Unfortunately, yes.

A certain percentage of the population is very sensitive to Retinol. It can cause cells to peel off and skin to appear dry, red and flaky.

Some dermatologists say that Retinol doesn’t usually cause an allergy, and it is more likely an irritation. In their attempt to solve that, the cosmetic producers had encapsulated the retinoids so that is released gradually and it is less likely to cause irritation.

It is always a better idea to start with lower concentration and let your skin some time to adapt it. Use a moisturizer to eliminate side effects and potentially cut back on the number of times you apply Retinol a week.

Some people are sensitive even to low levels of retinol but in reality, they can be allergic to almost anything. They should look for other ingredients with similar effect (beta-carotene is such an ingredient but not as powerful).



With all the options available it can be tough to know which type of retinol is best for your needs. Try to also take a look to the rest of ingredients that might enhance the benefits of your Retinol moisturizer, gel or serum.



We invite you to discover the Gerovital H3 Retinol line and decide if can be answer to your skin problems



They also help reduce acne outbreaks by preventing dead cells from clogging pores. By clearing acne and reducing outbreaks, they may also reduce the formation of acne scars. An oral retinoid also helps treat oil production, bacteria associated with acne, and inflammation.



Source:

www.markastore.com

dermatology.about.com/

www.elle.com

www.dermadoctor.com/

www.allure.com

www.webmd.com

www.thedermreview.com/

www.prevention.com/

The first anti-aging brand in the world, Gerovital H3 Prof. Dr. Ana Aslan, reinvents itself with better looks and stronger anti-wrinkle capabilities.

Face serums are a fairly new addition to our skin care routines. They are thick liquid-like products with active ingredients like vitamins and anti-oxidants that are formulated with smaller molecules so they can penetrate deep into the skin.

Because of their concentrated ingredients, serums tend to be pricier that a moisturizer, so it is natural to ask: a serum, a moisturizer, or both? What is the best option for us?






Serum can treat a wide area of concerns whether is acne, photo-damage, premature aging, there is a serum up there that is right for you.

• You can use more than one serum to give your complexion a well-rounded approach to skin care and protection.
• Apply anti-wrinkle serum twice a day to receive the full benefits of its nutrients.
• Pair your serum with a sunscreen for best daily protection

An innovative fluid gel, specially designed for areas most fragile around eyes, around lips and forehead.

- Gatuline Expression
- Natural Clay
- Hyaluronic Acid
- Vitamin E







Perfect Anti-Aging Serum, $24.99, by Gerovital H3 Evolution
A best selling that dramatically counteracts all signs of aging, restoring vitality and radiance to the skin.
- Active ingredients:
- Gatuline Expression
- Hyaluronic Acid
- Superoxide Dismutase (SOD) - Also called “The Anti-Aging Super-Enzyme
- Trylagen
- GP4G


Snail Extract Repair Serum, $59.99, by Herbagen

What are sunscreens?
Sunscreens are products combining several ingredients that help prevent the sun's ultraviolet (UV) radiation from reaching the skin. Two types of ultraviolet radiation, UVA and UVB, damage the skin, age it prematurely, and increase your risk of skin cancer.

Most sunscreens with an SPF of 15 or higher do an excellent job of protecting against UVB. SPF — or Sun Protection Factor — is a measure of a sunscreen's ability to prevent UVB from damaging the skin. Here's how it works: If it takes 20 minutes for your unprotected skin to start turning red, using an SPF 15 sunscreen theoretically prevents reddening 15 times longer — about five hours.
The experts recommend an SPF of 15 or higher. SPF 15 filters out approximately 93 percent of all incoming UVB rays. SPF 30 keeps out 97 percent and SPF 50 keeps out 98 percent. They may seem like negligible differences, but if you are light-sensitive, or have a history of skin cancer, those extra percentages will make a difference. And as you can see, no sunscreen can block all UV rays.

Is the SPF the key?
But numbers can be deceiving: products with very high SPFs may also encourage individuals to neglect other photoprotective behaviors, like seeking the shade and wearing sun-protective clothing. By preventing sunburn, sunscreens with very high SPFs can create a false sense of security, prompting consumers to stay out in the sun longer. Sun damage (for example, UVA damage) can take place without skin-reddening doses of UV radiation, and even the best sunscreens should be considered just one vital part of a comprehensive sun protection regimen.



Protection spectrum and the applying play an equal important role.
Your sunscreen should be broad spectrum (all the harmful rays in the spectrum are blocked)
The Sun produces 2 types of radiation that sneaks to the ozone on to us: ultraviolet A rays age the skin, ultraviolet B rays burn the skin; both can cause cancer
You are only fully protected if your sunscreen says broad spectrum on the label


The FDA banned the terms waterproof and sweat proof. Mix water and sunscreen and the sunscreen loose power. The updated labels will tell you exactly how long the sunscreen is water resistant, so how often to reapply.
None of that counts if you use it wrong.
Should you wear sunscreen on a cloudy day? Yes, 80% of ultraviolet rays still get through the clouds. Those UV rays, the ones who create spots and wrinkles go right through glass.
Should you even wear sunscreen in the car? Absolutely!
What is the perfect amount to use? It takes approx one once of sunscreen to cover an average adult from head to toe, then you have to reapply every 2 hours even you stay dry.
The paler your skin, the more you risk a sunburn, but ultraviolet rays can cause irreversible damage to all skin tones.

Ingredients
In terms of ingredients, asually, at least three active ones are called for. These generally include PABA derivatives, salicylates, and/or cinnamates (octylmethoxycinnamate and cinoxate) for UVB absorption; benzophenones (such as oxybenzone and sulisobenzone) for shorter-wavelength UVA protection; and avobenzone, ecamsule (MexorylTM), titanium dioxide, or zinc oxide for the remaining UVA spectrum.

And there is always the ”natural way”:
Ingredients that Naturally Protect Us from the Sun
There are natural ingredients, some may be found in our kitchens, that work to protect us from over exposure to the sun. Many are oils that contain SPF properties such as:

• Raspberry Seed Oil. The highest of all natural ingredients, contains an estimated SPF of 30-50.
• Shea Butter. An excellent skin protectant with an SPF of approximately 6-10.
• Carrot Seed Oil. Carrot seed oil is an essential oil and has been estimated to contain SPF levels of 30.
• Wheat Germ Oil. While super nourishing for the skin, it too possesses a natural SPF of 20.
• Sesame oil, Coconut Oil, Hemp oil, Avocado oil, Soybean, and Peanut Oil. All contain SPF levels between 4-10.
However, none of these ingredients are necessarily adequate on their own to provide us protection for an all day experience.
In order to make your own sunscreen you really should add the natural mineral zinc oxide (and possibly titanium oxide) to your recipe. This will give you real power to reflect the sun’s ray, with minimal negative effects.

Common Myths:
Wearing sunscreen can cause vitamin D deficiency.
There is some controversy regarding this issue, but few dermatologists believe (and no studies have shown) that sunscreens cause vitamin D deficiency. Also, vitamin D is available in dietary supplements and foods such as salmon and eggs, as well as enriched milk and orange juice.

If it's cold or cloudy outside, you don't need sunscreen.
This is not true. Up to 40 percent of the sun's ultraviolet radiation reaches the earth on a completely cloudy day. This misperception often leads to the most serious sunburns, because people spend all day outdoors with no protection from the sun.

Eighty percent of your sun exposure comes as a child, so it's too late to do anything now.
It appears that this universally promoted idea was based largely on a misinterpretation. A recent multi-center study showed that we get less than 25 percent of our total sun exposure by age 18. In fact, it is men over the age of 40 who spend the most time outdoors, and get the highest annual doses of UV rays. And since adult Americans are living longer and spending more leisure time outdoors, preventing ongoing skin damage will continue to be an important part of a healthy lifestyle.

Source:
• Skin Cancer Foundation
• US Food and Drug Admin (FDA)
• Frugally Sustainable



SPF + Broad Spectrum = Healthy, Happy Fun in the Sun
http://www.youtube.com/watch?feature=player_embedded&v=cXbh1sz85-E

ASLAVITAL MINERALACTIV Anti-Wrinkle Eye Contour

Cream with Eco-Certified Goji Berry Extract and 100% Natural Clay is a revolutionary 2 in 1 product which fights against wrinkles around the eyes and removes signs of tiredness.

Its pearly texture has a double function: skin care, hiding and correcting the skin imperfections and in the same time, restoring the skin’s brightness and luminosity.

• Photo – Aging (the oxidative stress on the skin of the UV rays)
• Free radicals which cause structural and functional mutations of the cellular membranes, the alteration of polyunsaturated fatty acids, of proteins and cellular DNA
• The mitochondrial diminished capacity of generating and stocking energy in the ATP molecule

• SOD, also called “The Anti-Aging Super-Enzyme”, ensures the skin’s firmness on a long term, acting against the oxidative degradation and protecting the fibroblasts, the collagen and elastin protein chain responsible for the skin’s elasticity. SOD is the most active antioxidant enzyme, of natural origin.
• The TRYLAGEN acts against the wrinkles and ensures a softer, more elastic skin, stimulating the production of new collagen and elastin fibers, offering support for synthesis.
• GP4G regenerates the skin from within, as a source of pure energy which supplements the diminished capacity of the cells to regenerate and stock energy

The products meant for women aged 45+ are especially created to solve more complex skin problems caused by photo-aging and the diminishing estrogen production around menopause: accelerated loss of skin elasticity, deep wrinkles’ formation, dark spots occurrence. The products from this range are rich in nutrients and offer an emolliating feeling, a long lasting hydration and a visible increase in the skin tonus

Find the entire range of Gerovital H3 Evolution online at markastore.com - quick dispatch and delivery, very good prices and free samples for every order

• Avocado, jojoba vegetal oils, wheat and soy germs, beeswax and cocoa butter reestablish the skin’s hydrolipidic barrier, prevent premature ageing processes caused by free radicals, increase skin elasticity, suppleness and hydration level.
• Ceramidyl-Omega is a complete, active, vegetal ingredient, a unique mixture of essential fatty acids (Omega-3, Omega-6, Omega-9) and pure glucoceramides. Reduces wrinkles, improves the skin’s moisture level, elasticity and comfort.
• Aquaxyl is an exceptional moisturizing ingredient, preservative-free, allergen-free and genetically modified organisms free.
• Vitamins A and E improve skin elasticity and prevent cutaneous ageing processes.
• Cornflowers extract fights against dark circles and bags under the eyes

Gerovital H3 Injectable solution - intramuscular

Composition:
One ampoule contains:
- Procaine hydrochloride (100 mg)
- Benzoic acid (6 mg)
- Disodium phosphate dodecahydrate (0.5 mg)
- Potassium metabisulfite (5 mg)
- Distilled water for injectable solutions (up to 5 ml)

Pharmacotherapeutic group: Alimentary tract and metabolism. Tonic preparations. ATC code: A13 AN01

Therapeutic indications:
DEPRESSIVE SYNDROME: light and moderate depression, in precocious stages, especially when conventional therapy is not well-tolerated or it has contraindications;
PARKINSONIAN SYNDROMES: where it can be used in monotherapy or associated with other antiparkinsonian drugs, especially with dopaminergic agents;
OSTEOARTHRITIS: chronic degenerative rheumatism;
SYSTEMIC ARTERIOSCLEROSIS: with hypercholesterolemia, ischaemic heart disease, arteritis, cerebral atherosclerosis;
PROTECTION AGAINST AGING PHENOMENA;


Posology and method of administration:
Before starting the treatment with Gerovital® H3 it is compulsory to test individual sensitivity to procaine, as follows: 1 ml from the injectable solution of Gerovital® H3 will be administered subcutaneously and after 24 hours the test should be repeated with 1.5 ml solution intramuscularly. If any allergic reaction occurs, the treatment is not recommended.

DEPRESSIVE SYNDROME:
Injectable solution:
1-st week: 1 ampoule (5 ml) intramuscular injection/day, 3 times a week (i.e., on Monday, on Wednesday and on Friday);
2-nd week: 1.5 ampoules (7.5 ml) intramuscular injection/day, 3 times a week;
3-rd week: 1.5 ampoules (7.5 ml) intramuscular injection/day, 3 times a week;
4 - th week: 2 ampoules (10 ml) intramuscular injection/day, 3 times a week.
The treatment should be repeated 4-6 times a year.
Total treatment: aprox 110 ampolules/year

PARKINSONIAN SYNDROMES:
Injectable solution: 1 ampoule (5 ml) intramuscular injection/day for 15 days
Total treatment: aprox 180 ampolules/year
Sugar-coated tablets: 2 tablets/daily for 15 days
Total treatment: aprox 360 tablets/year

OSTEOARTHRITIS:
Injectable solution: 1 ampoule (5 ml) intramuscular injection/ day, for 15-21 days and then
1 ampoule (5 ml) intramuscular injection/3 times a week (every other day), for 4 weeks;
The treatment should be repeated 4-5 times a year.
Total treatment: aprox 160 ampolules/year
Sugar-coated tablets: during the pauses in injections series, 1-2 tablets/day for 12-18 days/month, can be administrated.
Total treatment: aprox 180 tablets/year

SYSTEMIC ARTERIOSCLEROSIS:
Depending of the intensity and the localization of the process, the treatment should be as follows:
Injectable solution: 1 ampoule (5 ml) intramuscular injection/day 3 times a week for 4 weeks.
The treatment should be repeated 5-6 times a year.
Total treatment: aprox 72 ampolules/year
Sugar-coated tablets: between the injections series, oral treatment may be added - 2 sugar-coated tablets/day, 12 days.
Total treatment: aprox 150 tablets/year
Sugar-coated tablets: in some cases the treatment can be exclusively oral; 3 sugar-coated tablets/day, 21 days in 6-8 series/year
Total treatment: aprox 500 tablets/year

PROTECTION AGAINST AGING PHENOMENA:
Injectable solution: 1 ampoule (5 ml) intramuscular injection/day, 3 times a week (one ampoule every other day), over a period of 4 weeks
Total treatment: aprox 100 ampolules/year
Sugar-coated tablets: 2 sugar-coated tablets/ day, after meals, in the morning and in the afternoon, for 12 days.
Total treatment: aprox 150 tablets/year
Series of injections and sugar-coated tablets should be alternated yearly, continuously or with one-month pause between them. The schedule and the frequency of pauses will be decided by the geriatrist, according with the aging status of the patient.


Contraindications:
*Hypersensitivity to procaine in antecedents or tested.
*Severe arterial hypotension.
*Associated treatment with sulfonamides (except the antidiabetic ones) and with acetylcholinesterase agents: neostygmine, eserine (physostigmine) and pyridostigmine.

Precautions regarding medicinal product administration:
Before starting the treatment, a test for individual tolerance to procaine should be made (see under Posology and method of administration).
The treatment must take place under medical supervision, mainly in the first series of treatment, in order to establish the optimal dose.
The product should be administered with caution in patients with orthostatic hypotension.
Although procaine medication is not carcinogenic, it is not recommended to the patients with cancer, as its stimulating effect on mitotic potential of the neoplasic cell is not excluded.

Interactions with other medicinal products or other substances:
Gerovital® H3 should not be administered simultaneously with sulphonamides (antagonistic mechanism of action) - except the antidiabetic ones, anticholinesterases: neostygmine, eserine (physostigmine) and pyridostigmine.

Special warnings:
Pregnant and breast-feeding women: the studies on animals did not show teratogenic effects. In absence of teratogenic effects on animals, malformative effects on humans are not expected. However, the clinical experience with Gerovital® H3 is mainly on patients over the procreation period. For these reasons we do not recommend the use of the product during pregnancy and lactation.
Potential effect on the ability to drive or to use machines: the product does not interfere with these abilities.

Adverse reactions, which can occur during the use of the medicinal product:
Administration of Gerovital® H3 may produce allergic reactions in patients with hypersensitivity to procaine like skin rash or pruritus.
These effects impose an immediate stop of the treatment.
Minor effects may occur especially at the beginning of the treatment like: dizziness, weakness and palpitations. These effects can be avoided if after the injection the patient rests in bed for 10-15 minutes.

Overdose:
There are no reports of overdose related to administration of Gerovital® H3. In case of accidentally injection of high doses, severe hypotension, convulsions, coma, respiratory arrest may occur.
The treatment is symptomatic and support of vital functions.

Storage:
*Store below 25 C.
*Keep out of the reach of children.
*Do not use after the expiry date printed on the package.


Packaging:
Folding box with 5 brown ampoules of 5 ml

Manufacturer, name and country:
ZENTIVA N.V., Romania.

Buy Online: markastore.com - Official online Romanian retailer for Gerovital products